This document presents the priorities proposed by the Presidium to the European Pharmacopoeia Commission (EPC) for 2023-2025. They are the outcome of a discussion between the Chair, the two Vice-Chairs, the EDQM Director and the European Pharmacopoeia (Ph. Eur.) Secretariat. These priorities follow on from those established for 2019-2022 and take into account the achievements of the past three years, and the outcomes of the International conference Collaboration, Innovation and Scientific Excellence: the European Pharmacopoeia 11th Edition, organised by the EDQM in September 2022 in Strasbourg (hereinafter referred to as “11th Ed. Conference”).