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• New Ph. Eur. reference standards
• Replacement batches for Ph. Eur. reference standards
• Removal
• Future removal
• Change of sales units
• Information on change of price
• Change of EDQM storage/shipping conditions

See also:

• Content of the Ph. Eur. RS catalogue
• How to place an RS order

The EDQM announces the availability of:

• 9 new European Pharmacopoeia (Ph. Eur.) reference standards:

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• 22 replacement batches for Ph. Eur. reference standards:

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Information on reference standards removed from catalogue

• Supplement 10.4

Following the implementation of Supplement 10.4, the following standards are officially withdrawn from 1 April 2021.

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• Supplement 10.5

Following the implementation of Supplement 10.5, the following standards are officially withdrawn from 1 July 2021.

Information on reference standards with a future removal from catalogue

• Supplement 10.6

Following the implementation of Supplement 10.6 (1 January 2022), the following standards will be removed from the catalogue.

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The following standards will also be removed and replaced.

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Information on change of sales units

Cholesterol CRS, C2155000 – As of 6 July 2021, the sales unit is changed from one unit to two.

Information on change of price

Please note the price change for Batch 2 of Everolimus CRS and Everolimus for impurity C identification CRS, to €300 per sales unit.

Information on change of EDQM storage/shipping conditions

Based on new stability information, storage and shipping conditions will be simplified on 15 July 2021 for the following reference standard:

• Beta-sitosterol (Y0001615) CRS batch 1 will be stored at +5°C (previously –20°C) and shipped at ambient temperature (previously Ice –20°C).

Due to a stability issue, storage and shipping conditions have been modified, as of 17 June 2021, for the following reference standard:

• Benzylpenicillin for system suitability (Y0001889) CRS batch 1 is stored at –20°C (previously +5°C) and shipped under Ice –20°C (previously ambient).

Due to a stability issue, shipping conditions have been modified, as of 1 July 2021, for the following reference standard:

• Prilocaine (P2939000) CRS batch 2 is shipped under Ice +5°C (previously ambient).

NEW: Please be advised that as of July 2021, EDQM reference spectra will be sent exclusively by e-mail in PDF format and no longer in paper format by courier.

Therefore, within 48 hours of your order confirmation, you will receive a “Prior to dispatch” note and, in a separate e-mail, the PDF of your reference spectrum.

Please note that the PDF of the reference spectrum will be sent exclusively to the delivery contact stated on the order (in the “Delivered to” part of your Order confirmation). Only one delivery contact can be specified per order.

For any further information, please contact us via our HelpDesk.

Content of the European Pharmacopoeia RS catalogue

The EDQM proposes more than 3 000 Ph. Eur. RS including a wide range of highly characterised chemical reference substances (CRS), herbal reference standards (HRS) and biological reference preparations (BRP), as well as reference spectra for the tests and assays to be carried out in accordance with the official methods prescribed in the Ph. Eur.

The Ph. Eur. RS catalogue is updated on a daily basis and gives access not only to all the Ph. Eur. RS, but also to:

• Batch Validity Statements (BVSs) for each reference standard;
• Safety Data Sheets and Safety Data Statements for hazardous biologicals;
• leaflets (downloadable PDFs).

For your convenience, the Ph. Eur. RS catalogue is published daily and can be downloaded in in PDF format and in XML format.

When stocks of a given reference standard are low, the EDQM reserves the right to limit the quantities sold to each user to ensure that as many users as possible will receive at least some of the quantities available. Restrictions on quantities are applied at the time the purchase order is received.

Following a request from many users, the quantity allowed for each user is now directly displayed in the detailed view of the online catalogue.

How to place an RS order

If you wish to place an order, you can send your request to the EDQM either:

• via the WebStore;
• or by e-mail to [email protected] (in this case, please ensure that your order, on your company letterhead, states both the catalogue code and substance name and is attached to your e-mail).

A video “How to place an order through the reference standards WebStore” is available to help user ordering through the RS WebStore.

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