Vaccines for Human Use

Diphtheria vaccine

- Validation of a serological method using Vero cells

Study code: BSP006 / Study type: Refinement, Reduction

- Validation of a serological method combined with Tetanus vaccines

Study code: BSP034 Phase 1 / Study type: Refinement, Reduction

- Validation of a serological method combined with Tetanus vaccines

Study code: BSP034 Phase 1 Ext / Study type: Refinement, Reduction

- Validation of a serological method combined with Tetanus vaccines

Study code: BSP034 Phase 2 / Study type: Refinement, Reduction

Tetanus vaccine

- Validation of a serological method

Study code: BSP019 Phases 1 & 2 / Study type: Refinement, Reduction

- Validation of a serological method combined with Diphtheria vaccines

Study code: BSP035 : Phase 3 / Study type: Refinement, Reduction

- Establishment of a reference preparation for use in a new serological assay

Study code: BSP045 / Study type: Refinement, Reduction

Pertussis vaccine

- Standardisation of an in vivo assay for detection of residual pertussis toxin

 Study code: BSP076 / Study type: Refinement, Reduction

- Validation of a serological assay for acellular pertussis vaccines

 Study code: BSP083 / Study type: Refinement, Reduction

- Validation of a serological assay (Kendrick test)

 Study code: ECVAM-BSP (pre-BSP104)

 Study type: Refinement, Reduction

Hepatitis A vaccine

- Validation of an in vitro method and establishment of the corresponding reference preparation

Study code: BSP016 / Study type: Replacement

Inactivated Poliovirus vaccine (IPV)

- Standardisation of the rat bioassay

 Study code: BSP021 / Study type: Refinement

- Standardisation of an in vitro assay

 Study code: BSP023 / Study type: Replacement

Vaccines for Veterinary Use

Veterinary Clostridial vaccine

- Establishment of a reference antiserum (multicomponent) for serological and immunochemical assays

Study code: BSP022 / Study type: Refinement, Replacement

- Collaborative study for the validation of cell line assays for in-process toxicity and antigenicity testing of Clostridium septicum vaccine antigens – Part 1

Study code: BSP130 / Study type: Replacement

- Establishment of 2 reference preparations for use in a new serological assay

Study code: BSP024 / Study type: Refinement, Reduction

Swine erysipelas vaccine

- Validation of a new serological assay & establishment of a reference preparation

Study code: BSP038 / Study type: Refinement, Reduction

 Newcastle disease vaccine

- Validation of an in vitro assay & establishment of a reference preparation Phase 1

Study code: BSP055 / Study type: Replacement

- Validation of an in vitro assay & establishment of a reference preparation Phase 2

Study code: BSP055 / Study type: Replacement

Rabies vaccine

- Validation of a serological assay

Study code: BSP105 / Study type: Refinement