BSP programme for 3Rs
Vaccines for Human Use
Diphtheria vaccine
- Validation of a serological method using Vero cells
Study code: BSP006 / Study type: Refinement, Reduction
- Validation of a serological method combined with Tetanus vaccines
Study code: BSP034 Phase 1 / Study type: Refinement, Reduction
- Validation of a serological method combined with Tetanus vaccines
Study code: BSP034 Phase 1 Ext / Study type: Refinement, Reduction
- Validation of a serological method combined with Tetanus vaccines
Study code: BSP034 Phase 2 / Study type: Refinement, Reduction
Tetanus vaccine
- Validation of a serological method
Study code: BSP019 Phases 1 & 2 / Study type: Refinement, Reduction
- Validation of a serological method combined with Diphtheria vaccines
Study code: BSP035 : Phase 3 / Study type: Refinement, Reduction
- Establishment of a reference preparation for use in a new serological assay
Study code: BSP045 / Study type: Refinement, Reduction
Pertussis vaccine
- Standardisation of an in vivo assay for detection of residual pertussis toxin
Study code: BSP076 / Study type: Refinement, Reduction
- Validation of a serological assay for acellular pertussis vaccines
Study code: BSP083 / Study type: Refinement, Reduction
- Validation of a serological assay (Kendrick test)
Study code: ECVAM-BSP (pre-BSP104)
Study type: Refinement, Reduction
Hepatitis A vaccine
- Validation of an in vitro method and establishment of the corresponding reference preparation
Study code: BSP016 / Study type: Replacement
Inactivated Poliovirus vaccine (IPV)
- Standardisation of the rat bioassay
Study code: BSP021 / Study type: Refinement
- Standardisation of an in vitro assay
Study code: BSP023 / Study type: Replacement
Vaccines for Veterinary Use
Veterinary Clostridial vaccine
- Establishment of a reference antiserum (multicomponent) for serological and immunochemical assays
Study code: BSP022 / Study type: Refinement, Replacement
Study code: BSP130 / Study type: Replacement
- Establishment of 2 reference preparations for use in a new serological assay
Study code: BSP024 / Study type: Refinement, Reduction
Swine erysipelas vaccine
- Validation of a new serological assay & establishment of a reference preparation
Study code: BSP038 / Study type: Refinement, Reduction
Newcastle disease vaccine
- Validation of an in vitro assay & establishment of a reference preparation Phase 1
Study code: BSP055 / Study type: Replacement
- Validation of an in vitro assay & establishment of a reference preparation Phase 2
Study code: BSP055 / Study type: Replacement
Rabies vaccine
- Validation of a serological assay
Study code: BSP105 / Study type: Refinement
Blood Products
Tetanus Immunoglobulin
- Validation of 2 in vitro alternative assays
Study code: BSP079 / Study type: Replacement
Biologicals
Somatropin
- Establishment of a CRS for the use of physico-chemical methods
Study code: BSP004 / Study type: Replacement