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WHO ICRS Orders & Catalogue

EDQM / WHO ICRS Collaboration

The EDQM and the World Health Organization (WHO) are pleased to announce that EDQM is responsible for the distribution of WHO's International Chemical Reference Substances (ICRS).

The EDQM takes over responsibility for the establishment, preparation, storage and distribution of WHO ICRS from Apoteket AB, previously the WHO Collaborating Centre for ICRS. Reference material that was held and distributed by Apoteket AB will now be distributed by the EDQM.

ICRS are adopted by the WHO Expert Committee on Specifications for Pharmaceutical Preparations. They are supplied primarily for use in physical and chemical tests and assays described in the specifications for quality control of drugs published in the International Pharmacopoeia.

The EDQM will also organise international collaborative studies to establish new standards when required with WHO's assistance.


Online Database

Please consult the International Chemical Reference Substances database to:

  • Find if a standard is available
  • Download the leaflet and safety data sheet


Search ICRS Reference Standards

Place an order

If you wish to place an order, you can send your request to us:

  • using the web store. The form can also be used to confirm a proforma invoice or a quotation you have already received from the EDQM.
  • by email to – Please ensure that your order is on your company letter headed paper stating both the catalogue code and substance name and attached to your email.

Please select only one of the above options for sending your order and do not submit it multiple times via email, fax or online.

Before ordering we would advise to check the availability of the reference standards in our online database and to also read our Terms and Conditions.

For more detailed instructions about ordering, please read How to order reference standards.

Quotation requests

If you exceptionally need a quotation, you can send your request by email (see Place your order above) or complete this form.



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